Summary
September 2007, Vol. 8, No. 13, Pages 2001-2009 , DOI 10.1517/14656566.8.13.2001

Preventing cardiovascular and renal complications in the management of hypertension and metabolic syndrome

Jing Chen1 MD & Raymond R Townsend2 MD
1Tulane University, New Orleans, LA, USA
2University of Pennsylvania, 210 White Building, 3400 Spruce Street, Philadelphia, PA 19104, USA +1 215 662 2688; +1 215 662 3459;
Author for correspondence



This editorial discusses the history, definition and prevelance of the metabolic syndrome. Pathophysiological factors, such as girth, blood pressure, glucose, triglycerides, HDL-cholesterol, obesity, raised levels of plasma insulin and insulin resistance are outlined as being components of the syndrome. The paper examines the relationship of cardiovascular and all-cause mortality to the metabolic syndrome, and discusses the risk of cardiovascular disease associated with the metabolic syndrome. In addition, the article explores the link between metabolic syndrome, kidney function, insulin resistance and chronic kidney disease. Finally, the article discusses the issue of managing metabolic syndrome.

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Authors:
Jing Chen
Raymond R Townsend
Keywords:
cardiovascular disease
hyperfiltration
insulin
metabolic syndrome components