Summary
March 2008, Vol. 13, No. 1, Pages 53-62 , DOI 10.1517/14728214.13.1.53

Emerging therapies for fibromyalgia

Jacob N Ablin1 MD & Dan Buskila2 MD
1Tel Aviv Sourasky Medical Center, Rheumatology Institute, Tel Aviv, Israel
2Director Soroka Medical Center, Department of Medicine H, P.O. 151, Beer Sheva 84101, Israel
Author for correspondence



Background: Fibromyalgia syndrome (FMS) is a disorder characterized by widespread pain, tenderness, and fatigue. High prevalence marks the syndrome which is considered to reflect altered central pain processing. Fibromyalgia syndrome runs a chronic, non-progressive course, extracting high price owing to impaired quality of life, restricted vocational capacity, and increased health care utilization. Objective: To review current and emerging trends in the treatment of FMS. Methods: A rigorous search of published literature, abstract presentations, and industry provided data was performed. Results/conclusion: The recent FDA approval of pregabalin as a first specific medication for FMS may herald a new era for the development of medications with higher specificity and efficacy for this hitherto frustrating condition.

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Authors:
Jacob N Ablin
Dan Buskila
Keywords:
dopamine agonists
fibromyalgia
growth hormone
melatonin
reuptake inhibitors
α2δ ligands