Summary
March 2007, Vol. 11, No. 3, Pages 273-278 , DOI 10.1517/14728222.11.3.273

Mechanisms of action of statins in stroke

José Tuñón1,2, José Luis Martín-Ventura3, Luis Miguel Blanco-Colio3 & Jesús Egido4,5
1Associate Chief, Fundación Jiménez Díaz, Department of Cardiology, Avenida Reyes Católicos 2, 28040 Madrid, Spain
2Associate Professor, Autónoma University, Madrid, Spain
3Researcher, Fundación Jiménez Díaz, Vascular Research Laboratory, Avenida Reyes Católicos 2, 28040 Madrid, Spain
4Director, Fundación Jiménez Díaz, Vascular Research Laboratory, Avenida Reyes Católicos 2, 28040 Madrid, Spain.
5Professor of Medicine, Autónoma University, Madrid, Spain
Author for correspondence



Statins decrease the incidence of cardiovascular events and death in patients with coronary artery disease. Moreover, the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study has recently demonstrated that high-dose atorvastatin may also reduce the recurrence of stroke in patients with previous stroke or transitory ischemic attack.

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Online publication date: 1-Nov-2008.
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Authors:
José Tuñón
José Luis Martín-Ventura
Luis Miguel Blanco-Colio
Jesús Egido
Keywords:
atherothrombosis
statin
stroke