|
Summary
March 2007, Vol. 4, No. 2, Pages 101-110
, DOI 10.1517/17425247.4.2.101
Mesoporous silicon: a platform for the delivery of therapeuticsClive A Prestidge1Professor, University of South Australia, Ian Wark Research Institute, Australia 2PostDoctoral Researcher, University of South Australia, Ian Wark Research Institute, Australia 3Senior Scientist, pSiMedica Ltd, Malvern Hills Science Park, Geraldine Rd, Malvern, WR14 3SZ, UK 4Pharmaceutical Research Manager, pSiMedica Ltd, Malvern Hills Science Park, Geraldine Rd, Malvern, WR14 3SZ, UK. christianbarnett@psivida.com 5Senior Scientist, pSiMedica Ltd, Malvern Hills Science Park, Geraldine Rd, Malvern, WR14 3SZ, UK 6CSO, pSiMedica Ltd, Malvern Hills Science Park, Geraldine Rd, Malvern, WR14 3SZ, UK †  Author for correspondenceNanostructuring materials can radically change their properties. Two interesting examples highlighted here are nanoscale porosity inducing biodegradability, and nanoscale confinement affecting the physical form of an entrapped drug. Mesoporous silicon is under increasing study for drug-delivery applications, and is the topic of this review. The authors focus on those properties of most relevance to this application, as well as those recent studies published on small molecule and peptide/protein delivery. Forward Links to Citing ArticlesQingmin Ji, Somobrata Acharya, Jonathan P. Hill, Ajayan Vinu, Suk Bon Yoon, Jong-Sung Yu, Kazutami Sakamoto, Katsuhiko Ariga. (2009) Hierarchic Nanostructure for Auto-Modulation of Material Release: Mesoporous Nanocompartment Films. Advanced Functional Materials 19:11, 1792-1799 Online publication date: 9-Jul-2009. CrossRef C. A. Prestidge, T. J. Barnes, A. Mierczynska-Vasilev, I. Kempson, F. Peddie, C. Barnett. (2008) Peptide and protein loading into porous silicon wafers. physica status solidi (a) 205:2, 311-315 Online publication date: 1-Mar-2008. CrossRef Chongmu Lee, Hohyeong Kim, Chanseok Hong, Mina Kim, S. S. Hong, D. H. Lee, Wan In Lee. (2008) Porous silicon as an agent for cancer thermotherapy based on near-infrared light irradiation. Journal of Materials Chemistry 18:40, 4790 Online publication date: 1-Feb-2008. CrossRef C. A. Prestidge, T. J. Barnes, A. Mierczynska-Vasilev, W. Skinner, F. Peddie, C. Barnett. (2007) Loading and release of a model protein from porous silicon powders. physica status solidi (a) 204:10, 3361-3366 Online publication date: 1-Nov-2007. CrossRef L T Canham. (2007) Nanoscale semiconducting silicon as a nutritional food additive. Nanotechnology 18:18, 185704 Online publication date: 9-Jun-2007. CrossRef Users who read this article also read:
|
|
TOC Alert